Form
Lyophilized powder
Purity
>=99% (HPLC)
Molecular Weight
2888.3 Da
Storage
2-8C, protected from light
Use
For research purposes only. Not for human or animal use.
CAS
77591-33-4
Sequence
Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser
Longevity
TB-500
$80.00
99%+ Purity
Lab Tested
Research Grade
Lyophilized
COA Available
Fast Shipping
About This Compound
TB-500
TB-500 10mg — Research Overview
TB-500 is a synthetic peptide derived from the active region of Thymosin Beta-4 (Tβ4), a protein expressed in virtually all human and animal cells. The key active sequence Ac-LKKTETQ is responsible for Tβ4 actin-binding activity and is studied for its roles in cell migration, tissue regeneration, angiogenesis, and anti-inflammatory signaling.
Neogenesis Bio Labs supplies TB-500 as a lyophilized peptide at ≥99% purity, verified by third-party HPLC and mass spectrometry analysis.
What Researchers Study TB-500 For
- Cell Migration and Proliferation — actin-binding pathway, cytoskeletal regulation, and directed cell movement studies
- Tissue Regeneration — wound healing, muscle, tendon, and cardiac tissue repair pathway research
- Angiogenesis — new blood vessel formation, VEGF pathway interaction, and endothelial cell migration studies
- Anti-Inflammatory Research — cytokine modulation and inflammation resolution pathway studies
- Cardiac Repair — cardiomyocyte protection, cardiac progenitor cell activation, and myocardial repair research models
- Systemic Repair Signaling — non-local tissue repair signaling models across multiple tissue types
Frequently Asked Questions
What is the relationship between TB-500 and Thymosin Beta-4?
Thymosin Beta-4 is a 43-amino acid protein. TB-500 corresponds to the central active fragment containing the actin-binding sequence Ac-LKKTETQ. This region is responsible for most of the observed biological activity in cell migration and repair research.
How does TB-500 differ from BPC-157 in research models?
BPC-157 is primarily studied for local tissue repair and angiogenesis at the site of injury with strong gastroprotective backing. TB-500 is associated with broader, systemic cell migration and repair signaling through actin modulation. The two are frequently co-studied as complementary mechanisms.
What reconstitution approach is standard?
Lyophilized TB-500 is typically reconstituted with bacteriostatic water. Store at or below 4°C and use within 28 days. Store lyophilized powder at 2-8°C prior to reconstitution.
Is a Certificate of Analysis included?
Yes. Every vial ships with a third-party COA confirming compound identity, purity (≥99% HPLC), and peptide integrity.
For Research Use Only. TB-500 supplied by Neogenesis Bio Labs is intended exclusively for in-vitro research, laboratory study, and scientific investigation. Not for human consumption, veterinary use, or clinical application.
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