Form
Lyophilized powder
Purity
>=99% (HPLC)
Molecular Weight
663.4 Da
Storage
2-8C, protected from light and moisture
Use
For research purposes only. Not for human or animal use.
CAS
53-84-9
Longevity
NAD
$135.00
99%+ Purity
Lab Tested
Research Grade
Lyophilized
COA Available
Fast Shipping
About This Compound
NAD
NAD+ 1000mg — Research Overview
NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme present in every living cell, fundamental to cellular energy metabolism, DNA repair, and longevity-associated signaling pathways. As a critical hydride transfer agent and substrate for sirtuin and PARP enzymes, NAD+ occupies a central position in cellular biology research. Declining intracellular NAD+ levels with age have made it one of the most studied compounds in longevity and metabolic science.
Neogenesis Bio Labs supplies NAD+ as a high-purity lyophilized powder at ≥99% purity, verified by third-party HPLC analysis.
What Researchers Study NAD+ For
- Cellular Energy Metabolism — mitochondrial function, ATP production, and oxidative phosphorylation pathway studies
- DNA Repair Mechanisms — PARP enzyme activation, base excision repair, and genomic stability research
- Sirtuin Activation — SIRT1-7 deacetylase pathway and longevity-associated gene expression studies
- Circadian Rhythm Research — CLOCK gene regulation and metabolic oscillation pathway studies
- Neurological Pathways — neuroprotection, axonal integrity, and mitochondrial health in CNS research models
- Aging Biology — NAD+ decline, precursor supplementation research, and healthspan pathway studies
Frequently Asked Questions
What is NAD+ and why does it decline with age?
NAD+ is a dinucleotide coenzyme required for over 500 enzymatic reactions in human metabolism. Research suggests intracellular NAD+ levels decline approximately 50% between ages 40-60, associated with reduced mitochondrial efficiency, increased DNA damage, and declining sirtuin activity.
How does NAD+ relate to sirtuin research?
Sirtuins (SIRT1-7) are NAD+-dependent deacetylase enzymes that regulate gene expression, cellular stress responses, and metabolic adaptation. Their activity is directly limited by NAD+ availability, making NAD+ a critical variable in longevity pathway research.
How is NAD+ typically handled in research settings?
NAD+ powder is hygroscopic and should be stored sealed at 2-8°C or below, protected from light and moisture. For solution preparation, dissolve in appropriate aqueous buffer immediately before use. Reconstituted solutions should be used within 24-48 hours for optimal activity.
Is a Certificate of Analysis included?
Yes. Every order ships with a third-party COA confirming compound identity, purity (≥99% HPLC), and spectral verification.
For Research Use Only. NAD+ supplied by Neogenesis Bio Labs is intended exclusively for in-vitro research, laboratory study, and scientific investigation. Not for human consumption, veterinary use, or clinical application.
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