Form
Lyophilized powder
Purity
≥99% (HPLC)
Molecular Weight
5,135.9 Da
Storage
2-8°C, protected from light
Use
For research purposes only. Not for human or animal use.
CAS
218949-48-9
Sequence
Trans-3-hexenoic acid-Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Glu-Ser-Asn-Gln-Glu-Arg-Gly-Ala-Arg-Ala-Arg-Leu-NH2
Longevity
Tesamorelin
$70.00
99%+ Purity
Lab Tested
Research Grade
Lyophilized
COA Available
Fast Shipping
About This Compound
Tesamorelin
Tesamorelin 10mg — Research Overview
Tesamorelin is a synthetic analog of endogenous growth hormone-releasing hormone (GHRH), comprising the full 44-amino acid GHRH sequence stabilized with a trans-3-hexenoic acid group. This structural modification significantly enhances resistance to enzymatic degradation while preserving full biological activity at pituitary GHRH receptors. The result is a more stable, longer-acting GHRH analog compared to native GHRH or shorter fragments like Sermorelin.
Neogenesis Bio Labs supplies Tesamorelin as a lyophilized peptide at ≥99% purity, verified by third-party HPLC and mass spectrometry analysis.
What Researchers Study Tesamorelin For
- Growth Hormone Stimulation — pulsatile GH release via pituitary GHRH receptor activation, preserving natural hypothalamic feedback
- Visceral Adiposity Research — GH-mediated lipolysis effects on trunk and abdominal fat in metabolic models
- IGF-1 Axis Modulation — consistent elevation of insulin-like growth factor 1 without supraphysiologic GH spikes
- Body Composition — lean mass preservation concurrent with adipose tissue reduction in preclinical models
- Cognitive Function — emerging research on GH/IGF-1 axis effects on hippocampal activity, memory consolidation, and neuroplasticity markers
- Metabolic Biomarkers — lipid profile modulation, insulin sensitivity indices, and inflammatory marker research
Frequently Asked Questions
What makes Tesamorelin different from Sermorelin?
Sermorelin is a truncated GHRH fragment (amino acids 1-29). Tesamorelin contains the full 44-amino acid sequence plus a stabilizing modification, giving it greater receptor binding completeness and a longer effective half-life in research models.
How does Tesamorelin stimulate GH without being GH itself?
Tesamorelin binds GHRH receptors on pituitary somatotrophs, triggering endogenous GH synthesis and secretion. This preserves the natural GH pulse pattern and hypothalamic-pituitary feedback axis — fundamentally different from exogenous GH administration in research models.
Can Tesamorelin be combined with a GHRP in research models?
Research literature suggests GHRH analogs (acting on GHRH receptors) and GHRPs like Ipamorelin (acting on ghrelin receptors) work through complementary pathways. The combination is one of the most studied GH secretagogue stacks in preclinical research.
What reconstitution approach is used in research settings?
Lyophilized Tesamorelin is typically reconstituted with bacteriostatic water. Post-reconstitution stability is maintained for up to 28 days at or below 4°C. The lyophilized powder should be stored at 2-8°C prior to reconstitution.
Is a Certificate of Analysis provided?
Yes. Every Neogenesis Bio Labs Tesamorelin vial ships with a third-party COA confirming compound identity, purity (≥99% HPLC), and peptide integrity. Documentation available on request for institutional and B2B partners.
For Research Use Only. Tesamorelin supplied by Neogenesis Bio Labs is intended exclusively for in-vitro research, laboratory study, and scientific investigation. Not for human consumption, veterinary use, or clinical application. Must be handled by qualified research professionals in appropriate laboratory settings.
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